A Viral Nanoparticle with Dual Function as an Anthrax Antitoxin and Vaccine

Evaluation the Efficacy of Anthrax Vaccine against Challenge with a Highly Virulent Strain of Bacillus anthracis Isolated from Soil in Sheep, Goats and Guinea Pigs in Iran

  Protection of animals immunized against Bacillus anthracis is usually demonstrated by challenging with an appropriate dose of a strain of Bacillus anthracis that is lethal to unvaccinated animals inoculated at the same time. In this study the protective efficacy in anthrax vaccine (34F2 sterne strain spore) was evaluated in sheep, goats and guinea pigs challenged with subcutaneous inoculation...

Immunisation of Sheep and Goats with a Combined Clostridial and Anthrax Vaccine

Construction of a Eukaryotic Plasmid Encoding Bacillus anthracis Protective Antigen, a Candidate for DNA Vaccine

Background: DNA immunization with plasmid DNA encoding bacterial, viral, parasitic and tumor antigens has been reported to trigger protective immunity. Objective: To evaluate the use of a DNA immunization strategy for protection against anthrax, a plasmid was constructed. Methods: The partialsequence of protective antigen of Bacillus anthracis, amino acids 175-764, as a potent immunogenic targe...

Immunization of Cattle and Buffaloes With a Combined Anthrax, Haemorrhagic septicaemia and Blackleg Vaccine in Iran

Stability and potency studies of anthrax vaccine (Bacillus anthracis 34F2 Sterne strain) in Iran

  For evaluation the stability and potency of anthrax vaccine prepared in Razi Vaccine and Serum Research Institute in Iran, samples of different batches of vaccine were kept at 4-8 °C (refrigerator), 20-25 °C (room temperature) and 37 °C (incubator).The viable spores/ml of vaccines were determined using plate–counting method before and after holding at different temperatures monthly. Vaccine p...